Description:
Fluocinonide for fluorine containing synthetic, potent steroids. External use can make the dermal capillary contraction, inhibition of epidermal cell proliferation or regeneration, inhibit fibroblast connective tissues in the newborn, stable intracellular lysosomal membrane, anti-inflammatory, antipruritic effect. Absorbed through intact skin after topical. After absorption and system administration of corticosteroids in the body's metabolism, mainly in the liver metabolism, discharged by the kidneys. Fluocinonide is suitable for corticosteroid effective skin disease, such as eczema (especially infant eczema), neurodermatitis, skin pruritus, contact dermatitis, psoriasis, discoid lupus erythematosus, lichen planus, otitis externa, solar dermatitis. But need to pay attention to long-term or large area use can cause skin atrophy, telangiectasia, the occurrence of acne like dermatitis, perioral dermatitis, folliculitis, increased susceptibility to infection etc.. I can cause allergic contact dermatitis.
Properties white or white crystalline powder, odorless, tasteless. [alpha]D20+80 - +88 degrees (two oxygen six ring). Soluble in acetone, slightly soluble in ethanol, two oxygen six ring, insoluble in water and petroleum ether.
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